Previous studies have also demonstrated that EBERs induce the transcription of various cytokines depending on cell type, such as interleukin-10 (IL-10) in BL cells, insulin-like growth factor-1 (IGF1) in epithelial cells and IL-9 in T cells; these cytokines subsequently act as autocrine growth factors for the EBV-infected cancer cells [9,10,11,12]. This evidence concerns the gene IGF1 and cancer.