As a consequence, the inverse relationship between GAL3 and renal function, which we observed in our AHF patients, leads to the suggestion that increased plasma GAL3 in AHF might be linked to renal dysfunction, and the ability of GAL3 to predict outcomes in HF might reflect the consequences of renal impairment [3, 24, 25]. The gene discussed is LGALS3; the disease is Abnormal renal physiology.