Moreover, we found that vitamin D3 supplementation increased the lymphocyte : monocyte ratio, previously shown to be a marker of healing lesions [92], and accelerated the TB therapy-induced reduction in acute phase markers, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), and IFN-γ and IFN-γ-simulated chemokines CXCL9 and CXCL10. This evidence concerns the gene CRP and tuberculosis.