In addition, Zou et al. (194), through a meta-analysis that included 10 case–control studies, not only found that TLR4 Asp299Gly was associated with GC (OR: 1.87, 95% CI: 1.44–2.44), especially non-cardia GC (OR: 2.03, 95% CI: 1.51–2.72), but also gastric precancerous lesions (OR: 2.47, 95% CI: 1.57–3.88), especially in H. pylori-infected individuals (OR: 3.43, 95% CI: 1.92–6.13). This evidence concerns the gene TLR4 and gastric cancer.