Consistently, an ability of GILZ to suppress inflammation was demonstrated in a rat model of experimental autoimmune encephalomyelitis (EAE) using an amphipathic chariot peptide (Pep-1) for systemic administration of GILZ proteins or peptides (Srinivasan and Janardhanam, 2011). The gene discussed is TSC22D3; the disease is experimental autoimmune encephalomyelitis.