Furthermore, expression of S100A4 (Fsp1), a marker which is associated with EMT progression, and widely used to detect cells undergoing EMT, has been found to be expressed not only by subsets of fibroblasts but also by myeloid cells, suggesting that the role of this protein in the pathogenesis of liver fibrosis has to be reevaluated. This evidence concerns the gene S100A4 and Hepatic fibrosis.