CHRNA7 and memory impairment: The activation of the α7 nicotinic acetylcholine receptor/phosphatidylinositol 3-kinase (α7nAChR/PI3K) signaling pathway and a cross talk with the Wnt signaling pathway seems to mediate nicotine's positive effects on memory impairment in TgAPPswe/PS1dE9 mice (Inestrosa et al., 2013).