Drugs currently used to treat AD, such as acetylcholinesterase (AChE) inhibitors and the N-methyl-D-aspartate (NMDA) antagonists, have only modest effects in delaying the progression of the disease (Starkstein and Mizrahi, 2006; Hansen et al., 2007; Raina et al., 2008). The gene discussed is ACHE; the disease is Alzheimer disease.