NPY and anorexia nervosa: Thus, any deregulation of these actions, by an excess simultaneous secretion of the components or a non adequate integration of NPY and AgRP signals (Kas et al., 2005) for example, could lead to a blurred signal which could be fatal during the recovery period and may lead to an irreversible pathological state as the installation of anorexia nervosa (Inui, 2001).