CASP8 and cancer: The study concludes that Kuding tea polyphenols are able to inhibit cancer cells growth, slowing down BcaCD885 cell proliferation, upregulate the expression of caspase-3, caspase-8, caspase-9, Fas/FasL, Bax p53, p21, E2F1, p73 and down-regulate the expression of Bcl-2, Bcl-xL, HIAP-1, and HIAP-2.