They confirmed a significant increase in IL-17, IL-21, IL-22, and IL-23 serum levels in blood and BM in MM compared with healthy controls and that IL-17 promotes MM cell growth and colony formation via IL-17 receptor, adhesion to BM stromal cells and increased growth in the in vivo murine xenotransplant model of human MM cell lines. The gene discussed is IL21; the disease is Miyoshi myopathy.