CGA and pancreatic insulinoma: We noticed that only 3 of 56 patients with localized insulinomas had the CgA levels more than 120.8 ng/ml (i.e. two fold more than cut-off values for insulinoma), whereas 4 of 12 patients with localized non-insulinomas had CgA levels more than 242 ng/ml (also two fold more than cut-off values for non-insulinoma), P = 0.015 (Fisher exact), see Figure 6, indicating the patients with localized non-insulinomas had a more frequency of remarkable elevation of CgA than that in the patients with localized insulinomas.