Reanalysis of muscle transcriptomes from 12 different muscle diseases (GSE3307) with non-inflammatory myopathies except from juvenile dermatomyositis (JDM) revealed upregulation of PSMB8/-9 only in samples from JDM and in one out of four samples from limb girdle muscular dystrophy 2I (LGMD2I). Here, PSMB8 is linked to juvenile dermatomyositis.