A number of chemokines [CCL2, CCL3, CLL4, CCL8, CCL13, CCL19, chemokine (C-X-C motif) ligand (CXCL) 1, CXCL6, CXCL16] were upregulated in sensitized dogs after allergen challenge, similar to what is observed in human atopic dermatitis (Taha et al. 2000; Giustizieri et al. 2001; Kaburagi et al. 2001). This evidence concerns the gene CCL2 and atopic eczema.