ALB and acute respiratory distress syndrome: Increasingly, evidence points to the role of Cav-1 and caveolae-mediated transcellular albumin transport (transcytosis) in the pathogenesis of ALI in general [12,18-20,28,37,54] and VILI in particular [20], although it could also be shown that caveolin-1 deficient mice developed a more severe VILI than WT animals [22].