Additionally, Src-dependent phosphorylation of caveolin-1 on tyrosine 14, which is known to promote the transcellular transport of albumin via caveolae [17] as well as regulate downstream signaling that can lead to disruption of adherens junctions [18], also contributes significantly to the development of ALI [12,19,20]. The gene discussed is SRC; the disease is acute respiratory distress syndrome.