ANXA1 and cancer: It's worth noting that although annexin A1 (lipocortin1, ANXA1), a main targeted gene of miR-196a, was identified to be linked with increased multiple malignant tumors in brain models of ischemia and reperfusion injury, the SNP rs11614913 in miR-196a2C>T would not affect the function inhibiting targeted genes expression, because it was not present in the seed-sequences of miR-196a.