miR-27b was determined to target several lipid-associated genes in human hepatoma cell lines, for example heparan sulfate N-deacetylase/N-sulfotransferase 1 (NDST1), angiopoietin-like 3 (ANGPTL3), peroxisome proliferator-activated receptor γ (PPARG) and glycerol-3-phosphate acyltransferase 1 (GPAM). Here, ANGPTL3 is linked to hepatocellular carcinoma.