PDCD1 and HIV infectious disease: In order to provide more insights into the phenotype of CD8+ T-cells found in HIV infection, the expression of Programmed cell death 1 (PD-1), a molecule commonly linked to immune exhaustion, was evaluated on bulk and HIV-specific CD8+ T-cells from a subset of 19 PHI subjects using samples obtained at 8±1 months post-infection (due to cell sample availability).