APP and diabetes mellitus: However, three days after STZ administration, the blood glucose levels of diabetic rats (30.8 ± 1.6 mmol/L for DM group and 28.6 ± 1.6 mmol/L for APP group) were significantly higher than that of the control rats (7.1 ± 0.3 mmol/L, P < 0.0001) and maintained a higher level until the start of the electrophysiological recording.