Based on occurrence of mutation, OCA is identified as nonsyndromic OCA genes (TYR, OCA2, TYRP1, and SLC45A2) and syndromic OCA genes (HPS1, AP3B1, HPS3, HPS4, HPS5, HPS6, DTNBP1, BLOC1S3, PLDN, LYST, MYO5A, RAB27A, and MLPH) [4, 5]. The gene discussed is LYST; the disease is oculocutaneous albinism.