NFKB1 and neoplasm: In addition, the promoting effect of IL-6 on cancer growth can also be via an activation of NF-κB in the cancer cells [37]; we have shown that increased NF-κB was expressed in the transformed epithelial cells and tumor stromal cells over times and suggested that the interaction between NF-κB and IL-6 occurred during the procession of CAC in colitis mice.