Several risk factors may contribute to uterine rupture of the gravid uterus in women with no history of uterine surgery, including intrauterine surgery, multiparity, oxytocin stimulation, placenta accreta, Ehlers-Danlos syndrome, cocaine abuse, in-utero exposure to diethylstilbestrol, uterine anomalies, and obstructed labor, for instance, due to undiagnosed fetopelvic disproportion or malpresentation [1, 7, 9–14]. This evidence concerns the gene OXT and cocaine abuse.