The DEG cluster, whose expression wasincreased in PE, includes not only known candidate genes that have previouslybeen identified in many genome-wide studies of the expression profiles of theplacental genes in preeclampsia (e.g., LEP,BHLHB2, SIGLEC6, RDH13,BCL6), but also new potential candidate genes (CORO2A,SYDE1, PLIN2, CEBPA, HK2, NDRG1, ERRFI1, EFNB1, GFOD2, NCOR2, HMHA1, HERPUD1,KIF2A), whose association with the development of PE has beenestablished either in a few studies [16-21], or was done sofor the first time in our work. This evidence concerns the gene HK2 and preeclampsia.