Moreover, older men (age ≥61 years old) had higher mean ABCA1 DNA methylation levels than younger men (age <61 years old) (38.0 ± 1.2 versus 35.2 ± 1.0, P = 0.02; after consideration of CAD occurrence and current treatments) (Figure 1B). This evidence concerns the gene ABCA1 and coronary artery disorder.