Older men with CAD (age ≥61 years old; n = 19) showed significantly higher DNA methylation levels at the ABCA1 gene promoter locus compared to younger men without CAD (age <61 years old), older men without CAD (age ≥61 years old) and younger men with CAD (age <61 years old) (Table 1 and Figure 2), independently of current treatment. Here, ABCA1 is linked to coronary artery disorder.