Interestingly, it has been shown that EBNA3C and EBNA3A cooperate to repress expression of the proapoptotic tumor-suppressor BCL2L11 (BIM) in BL cell lines (15) and that EBNA3C can be recruited to the BIM promoter proximal to the transcription start site (TSS) (80). Here, BCL2L11 is linked to Burkitt lymphoma.