TMBIM4 and infection: After vv811 infection of the transduced cell lines, only B13 and F1 showed an anti-apoptotic effect (Fig. 4), indicating that B13 and F1 are more potent inhibitors than GAAP and N1 in this experimental system, and/or that vv811 infection triggered apoptotic responses in a manner that was not mimicked by the drugs employed in Fig. 3.