Although this general trend was also observed in our CRC sample cohort, with KRAS WT tumors demonstrating better DFS post-surgery than KRAS G12 mutant tumors, it was not significant due to the heterogeneity in the signaling pathways within each KRAS mutational subtype, especially in stage II and III CRC tumors regardless of whether or not the patients received chemotherapy. This evidence concerns the gene KRAS and colorectal carcinoma.