Major hypoglycemia (Table S2) was reported in only 2 patients receiving GLP-1 analogues (liraglutide 1.2 mg QD); and there was no difference in reported minor to moderate hypoglycemia (Table S2) between GLP-1 analogues and sitagliptin (relative risk 1.35, 95% CI 0.71–2.58) (Table 3). This evidence concerns the gene GLP1R and Hypoglycemia.