In the mice receiving sham operation, about 60% infection efficiency was obtained for the whole heart at 1 week after intramyocardial injection of Ad-Ankrd1 manifested by green fluorescence in cardiomyocytes under fluorescence microscopy as well as a significantly higher CARP expression level than in Ad-EGFP group (Fig. 2E and F). The gene discussed is ANKRD1; the disease is infection.