ERBB2 and invasive breast carcinoma: With the help of the MBB buffer, we determined the HER2 ECD levels in serum samples from invasive breast cancer patients (“breast ca”, N=28), non-invasive DCIS patients (“DCIS”, N=33), patients with benign breast disease (“benign”, N=11), as well as healthy controls (“control”, N=29) (Figure 1).