Among the best off, patients with morbid obesity (proportional shortfall = 0.17) were better off than patients with hip osteoarthritis (proportional shortfall = 0.18) according to the proportional shortfall as compared to the lifetime QALYs approach.Unilateral cochlear implants for childhood deafness yielded the highest gain (10.7 QALYs), and stroke units for acute stroke victims yielded the lowest gain (0.5 QALYs) (Figure 4).Note especially two condition-intervention pairs in Figure 2 through Figure 4: (A) rheumatoid arthritis/TNF inhibitor and (B) morbid obesity/gastric bypass. The gene discussed is TNF; the disease is morbid obesity.