In the light of these considerations, KGF positive effect on the viability of tamoxifen-treated cells, previously demonstrated by our group on breast cancer cell lines [37] and now confirmed also on HVMs, suggests that the administration of KGF for the relief of vaginal symptoms can be even more effective than the use of oestrogens, especially in oncological patients treated with tamoxifen or other chemotherapeutic drugs at anti-oestrogenic action. Here, FGF7 is linked to breast carcinoma.