HLA-C and pancreatic serous cystadenoma: Previous studies have reported that HLA-C∗06:02 has different effect sizes for PsA and PsC, naturally leading to a hypothesis that the heterogeneity is driven by the difference in HLA-C, the major risk factor.13–16,23 However, our observation is more concordant with a model where the two PsV subtypes generally share the same risk alleles, including HLA-C∗06:02, but differ at a specific locus that contributes to subtype differences.