TF and melanoma: Ectopic expression of TF has been detected in several type of cancers, including cervical cancers [18], epithelial ovarian cancer (EOC) [24], breast cancer [25], brain tumors [26], pancreatic cancer [27], gastric cancer [28], prostate cancer [29], colorectal cancer (CRC) [30], lung cancer [31], melanoma [32], and several cancer cell lines, including human promyelocytic leukemia tumor cell lines HL-60, glioma cell line U343, gastric cell line KATOIII, SNU-5 and MKN-74, colon cancer line HCT116, epidermoid carcinoma cell line A431, melanoma cell line WM1341B and WM938A [4],[33].