DGCR8 and 22q11.2 deletion syndrome: The lack of significant difference observed between individuals with 22q11DS compared to TD in the expression levels of two mirtrons, whose biogenesis depends on alternative, non-canonical, miRNA biogenesis pathways via splicing, in addition to higher expression levels of primary miRNA and of lower of mature miRNA of those found to be dysregulated in individuals with 22q11DS compared to TD, are supportive of the hypothesis that altered miRNA expression pattern observed in this study likely results from the hemizygous DGCR8 expression [56].