We induced sepsis and measured inflammatory readouts 24 h after CLP in mice that were doubly deficient in Nod1 and Nod2 (Nod1/Nod2) and in mice that were deficient in Rip2. Similar to Nod1- and Nod2- single deficient mice, neutrophil recruitment to the peritoneal cavity 24 h after CLP surgery was not different among WT, Nod1/Nod2- and Rip2-deficient mice (Figure 3a). The gene discussed is NOD2; the disease is Sepsis.