To confirm that the absence of a phenotype in Nod1- and Nod2-deficient mice during polymicrobial sepsis was not the consequence of a microbiotic variation in the knockout mice, we inoculated the cecal bacteria isolated from WT mice into the peritoneal cavities of WT, Nod1- and Nod2-deficient mice. The gene discussed is NOD2; the disease is Sepsis.