ESR1 and cancer: We also analyzed the correlation between lincRNA expression and the clinical feature of the cancer including the ages of original diagnosis (median 54 years, range 32–73 years), cancer staging (grade II or III), lymph node metastasis (positive or negative), ER/PR (estrogen and progesterone receptor level), the level of HER2 (positive or negative) and p53 protein (positive or negative).