INS and polycystic ovary syndrome: Since the effects of co-administration of MTF and NAC compared to MTF and NAC alone in reducing metabolic and hormonal factors such as insulin, leptin and MDA in patients with PCOS has not been evaluated yet, we have evaluated and compared the efficacy of co-treatment of MTF and NAC on clinical, metabolic and hormonal aspects during course of ovulation induction in PCOS individual undergoing ICSI cycle.