However, the reduction of AMH level in the treatment groups, which was close to be significant (p=0.051), is consistent with literature, so it has been suggested that long-term administration is required for a reduction in the raised AMH level observed in PCOS individuals (33), indicating that these drugs can reduced the number of AMH producing follicle which is appropriate for PCOS patient. Here, AMH is linked to polycystic ovary syndrome.