CAMK1 and Alzheimer disease: Moreover, due to the functional analogy, it should be interesting to study whether the CaMKK/CaMK1 axis regulates NFAT expression in addition to CaMKII in pathologies such as Alzheimer's disease, muscular hypertrophy or cancer progression and metastasis, where hyperactivation of NFAT has been detected (53,55,64–66).