The CC-chemokine receptor 4 (CCR4) is also highly expressed on tumor cells of T-cell derived variants of non-Hodgkin’s lymphoma (NHL), such as adult T-cell leukemia/lymphoma (ATLL) [13], [14], cutaneous T-cell lymphoma (CTCL) [15], [16], and other kinds of malignancies belonging to the heterogeneous group of peripheral T-cell lymphoma (PTCL) [17]. Here, CCR4 is linked to primary cutaneous T-cell non-Hodgkin lymphoma.