For example, over half of these genes have been previously associated with viral infection or replication, or have been found to physically interact with viral proteins (e.g. CLDN3 [40]; CRHR2 [41]; ILF2 [42], [43]; ILF3 [44], [45]; LTF [46]–[50]; miR-122 [51]; RCHY1 [52]; and, RUVBL2 [53]). The gene discussed is RCHY1; the disease is viral infectious disease.