FMR1 and Anxiety: Fmr1 KO mice spent more time in the extremity of open arms [genotype effect: F(1,77) = 5.31, p < 0.05] and this was corrected by BMS-204352 that also increased non-social anxiety in WT mice [treatment effect: F(1,77) = 4.06, p < 0.05; Figure 3b].