Although the function of VRK2 in schizophrenia is not well known, VRK2 rs2312147 C allele was reported to show a significant association with schizophrenia [European combined samples: odds ratio (OR) = 1.09, P = 1.9×10−9[5]; Asian combined samples: OR = 1.16, P = 4.24×10−4[9]]and VRK2 gene expression was up-regulated in the blood cells of patients with schizophrenia [9]. This evidence concerns the gene VRK2 and schizophrenia.