For instance, the Fanconi anemia complementation group M gene (FANCM) was initially discovered in one family with Fanconi anemia [17], but we did not observe any deficit of homozygous LoFs in FANCM from our dataset (expected = 5, observed = 7), which we would typically observe for a disease causing recessive variant. The gene discussed is FANCM; the disease is anemia (phenotype).