Hepatic cellular degeneration, degeneration of reticular fibres as shown in the silver impregnated liver section (Figure 2) and build up of collagen fibres as shown in the liver sections stained for presence of collagen (Figure 3) revealed the presence of hepatic fibrosis in the liver of STZ-diabetic rats and the insulin treated diabetic rats. Here, INS is linked to Hepatic fibrosis.