MYD88 and intestinal polyp: A correlation between the TLR/MyD88 signaling pathway and APC mutations was recently proposed (82, 83) since MyD88 signaling was found to facilitate the growth of intestinal polyps while the ablation of MyD88 restricted polyp growth in Apcmin/+/Myd88−/− mice, but not in Apcmin/+ mice (83, 84).