PPARGC1A and hydrops fetalis: Consistent with the regulatory role of PGC1A in substrate utilization [14], [53]–[56], perinatal DDT exposure and adult HF feeding decreased the expression of glucose transporter Glut4, lipoprotein transporter Lpl (no diet effect), lipolysis rate-limiting Pnpla, and the fatty acid oxidation shuttle Cpt2 (Fig. 5D–G).