We found three SNPs (rs2973034, rs2973034, rs78670708) in the TFBSs of a lincRNA, ENSG00000248587 (also known as GDNF-AS1), ENSG00000248587 has been demonstrated to be associated with Alzheimer disease [44]. The gene discussed is GDNF; the disease is early-onset autosomal dominant Alzheimer disease.