In the group of control pigs, unspecific symptoms were occasionally observed and led to euthanasia of one landrace pig at 7 dpi (dyspnea upon bleeding), and of one wild boar at 23 dpi (ruptured gall bladder, severe gastritis and enteritis).Parameters indicative for the B-cell populations in peripheral blood are summarized in Figure 2: The percentage of cells with CD2 + CD21+ phenotype (naïve B-cells) was down regulated in all infected groups. Here, CR2 is linked to enteritis.