Patients with a cardioembolic source of ischemic stroke had the highest s-cTnI levels compared to the other etiologies (0.007 [IQR 0.001–0.030] vs. 0.002 [IQR 0.000–0.008] μg/L, p<0.0001). The gene discussed is TNNI3; the disease is ischemic stroke.