Young infants had a lower post-vaccination anti-CS antibody GMT than children (anti-CS antibody GMT range across sites: 117 to 335 EU/ml, per-protocol population), and, in contrast to what was observed in children, higher anti-CS antibody titers were associated with lower malaria incidence (p<0.001) (Figures 18 and 19; Tables S11 and S16). Here, CS is linked to malaria.